Answer:
The great compromise of 1850 came into being a measure to tone down the difference between the north and the south with respect to slavery It was in the year 1820 via the missouri compromise that missouri was granted the permission to stay a slave state Hope this Helps!
Native Americans were generally disenfrachised, lost power, and were negatively impacted by American expansionism, also known as Manifest Destiny, in this time period.
Events such as the Trail of Tears force the removal of millions of Native Americans over time to unfamiliar land that was often not as suitable as the land they came from. They also died in large numbers due to war and disease.