Explanation:
At position 12 of G protein Ras there is a normal amino acid attached to it called Glycine. Which make Ras protein a highly controlled protein. However, there is another amino acid called aspartate at 12 position which make Ras vulnerable by the formation of weak GTPase enzyme activity and GTP binding. Which prevent Ras from turning off. This the reason why aspartate in oncogenic. Furthermore, weak binding of GTP has influence because its binding can not be hydrolyzed.
Reference Research Paper
Morris, K. M., Henderson, R., Suresh Kumar, T. K., Heyes, C. D., & Adams, P. D. (2016). Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor. Small GTPases, 7(1), 1-11.
Answer:
The Earth's outer crust (the lithosphere) is composed of a series of tectonic plates that move on a hot flowing mantle layer called the asthenosphere. Heat within the asthenosphere creates convection currents that cause tectonic plates to move several centimeters per year relative to each other.
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Answer:
Addition of nucleotides to form a complementary strand of DNA.
Explanation:
Replication of the genetic material (DNA) is a paramount process that must be undergone by any cell prior to its division. The series of processes that occurs to the DNA molecule during DNA replication is catalyzed by different enzymes with specific functions. However, one of these enzyme callee DNA POLYMERASE catalyzes the main event, which is the synthesis of a complementary strand.
DNA polymerase catalyzes the production of phosphodiester bonds that joins the nucleotides. The enzyme synthesizes a nuceleotide base complementary to the one on the template strand, to eventually form a new DNA strand. Hence, blocking the function of this enzyme is tantamount to blocking the synthesis of a new strand itself.
B) Because Hydroelectric energy does not create waste but could cause ecological impacts and flooding.
Answer:
Development.
Explanation:
Development includes the process of developing of all the characters of the living organisms. Development of an organisms depends on the internal as well as external factors.
The individuals can show physical development, mental development, social development and developments in terms of understanding, emotions and behavior of the individual depending on the different factors. The individual with several abnormality is unable to show proper development.
Thus, the answer is development.
