Insulin is produced by beta cells of the pancreas for storing and disposing of the glucose in various parts of the body like liver. This activity is a differentiated function of the beta cells of pancreas only. Although gene for insulin production is present in all cells, it is expressed only in the beta cells. Hence, it is a differentiated function.
Answer:
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Those mutated genes are most commonly recessive. Females have two X chromosomes so they can have a chromosome with the mutated gene and one with the healthy gene. The healthy gene is dominant so the disease won't manifest, and the woman is only a carrier. Males have only one X chromosome and an Y chromosome. If they have the mutated gene on the X chromosome they won't have another X chromosome with the healthy gene.
To summarize, men can't be carriers and they only need one copy of the mutated X-linked gene while women need two copies of the mutated gene.
Neural control of GFR is mediated by Sympathetic neurons that innervate alpha receptors on vascular smooth muscle causing Vasoconstriction.
<h3>How is GFR regulated?</h3>
- The sympathetic division of the nervous system regulates the GFR or Glomerular Filtration Rate.
- GFR is the sum total of filtration rates of all the working nephrons in the kidney.
- Sympathetic division comes into action when the mean arterial pressure is very low (below 80mmHg).
- In response to low blood pressure, the medulla releases norepinephrine through sympathetic nerves.
- Norepinephrine leads to activation of alpha receptors on arteries which cause vasoconstriction.
- Alpha receptors are more abundant on afferent arterioles.
- This leads to vasoconstriction (narrowing) of arteries supplying to the glomerulus.
- This decreases blood flow to glomerulus, leading to decrease in GFR.
Learn more about Glomerular Filtration Rate here:
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