Answer:
this note might help you :
Explanation:
If the enzyme changes shape, the active site may no longer bind to the appropriate substrate and the rate of reaction will decrease. Dramatic changes to the temperature and pH will eventually cause enzymes to denature.
Answer:
very few M. tuberculosis in the standard nutrient cell cultures carry the rpoB gene mutation, but almost all of the M. tuberculosis in the cell cultures with rifampin carry the rpoB mutation
When cell over divide they cause a sickness or cancer
