Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
To learn more about stroke with the help of given link:
brainly.com/question/26482925
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Answer:
Primary active transport
Explanation:
Active transport may be defined as the movement of particles against their concentration gradient with the help of an energy source like ATP. Two main types of active transport are secondary active transport and primary active transport.
Primary active transport includes the sodium potassium pump because it directly uses the stored chemical energy in the form of ATP. Three sodium moves out of the cell and two potassium moves inside the cell with the help of ATP.
Thus, the correct answer is option (a).
The original weight is 4.
Explanation:
20%= 1/5 if u don’t know the percentage then u can simply by doing..
20/100 then u divide it. U can do this by any other numbers such as 2, 4,5,10 and 20. U can do which ever way u like but i would recommend doing it either by 10 or 20.
So if we divide it by 20 we do...
20/100 divided by 20= 1/5
Or
20/100 divided by 10= 2/10
2/10 divided by 2 = 1/5
You can see the bigger the number that fits in is faster, although u can do it any way u feel like doing.
So we have got 1/5 from 20%. Now we do...
1/5 divided by 20. So when we do this, we use the bottom number to divide it and the top number to times it.
So..
1/5 u could use as 20 divided by 5..
Then 1 times the number that u get from ur before sum.
The answer is 4.
Because 1/5= 20 divided by 5 = 4
Since we have a 1 left we do..
4 times 1 which is... 4.
( u don’t need to show these parts in doing ur working, but i am doing these so they can help u understand)
So the answer is 4 and is the original weight.
I hope this is clear and helps u! :D
Answer:
has a high body fat percentage for his or her height
Answer:
The maxillary first molar normally has three roots. The mesiobuccal root is broad distobuccal and has prominent depressions or flutings on its mesial and distal surfaces. The internal canal morphology is highly variable, but the majority of the mesiobuccal roots contain two canals.
Explanation: