The increased heart failure risk and sudden cardiac death are associated with Pathological cardiac hypertrophy.
Many transcription factors and miRNAs were implicated in cardiac hypertrophy, and In gene expression regulation their high combinatorial action is becoming more clear. Parallel expression profiles for messenger RNA (mRNA) and miRNAs were integrated from an in vitro model of cardiac hypertrophy with experimentally validated interactions from seven curated databases in order to build the cardiac hypertrophy-related transcription factors -miRNA regulatory network. Based on Borda count aggregation of distinct network-based properties they suggested a completely unsupervised technique to identify core regulatory elements.
By combining node scores derived from active pathways, motif-based centrality, and k-shell index which was able to prioritize biologically meaningful transcription factors and miRNAs as central nodes in the point potential active and network regulatory pathways in cardiac hypertrophy. Moreover, we identified recurrent associations in the crosstalk feed-forward loop motifs between transcription factors and miRNAs.Most transcription factors and miRNAs were immersed in specific interconnection patterns.
To know more about transcription factors brainly.com/question/12150990?referrer=searchResults.
To know more about Pathological cardiac hypertrophy. brainly.com/question/15322836?referrer=searchResults.
#SPJ4
TOASTYYYYYYYYYYYYYYY and kidneys are orgins
Answer: In actuality, no organism will be able to replace the coral reefs.
Explanation: The climate change has made the waters warmer, this has hit the coral reefs really bad, they tend to lose colour and the capability to produce food. The coral reef tend to get bleached. They can struck to
- disease
- algae
- death
The acidification has increased the absorption of carbon dioxide which has compounded in the bleaching problem too.
when you think of the collapse, perhaps only corals which have developed a high resistance to the heat as well the acidification may remain but will they be the same. The answer is a no. None of the organisms or ecosystem can make up the functionality of the coral reefs.
Answer:
2) possess tubular or stalk-like extensions of their cells.
Explanation:
Appendages are tubular or stalk like extensions found on bacterial surface and utilized for specific function by bacteria. Some appendages are strongly anchored on surface while other are loosely attached.
Three important appendages in bacteria are;
Flagella; locomotion
Fimbriae; stick bacteria on the surface of host
Pili; Used in conjugation process for reproduction
A hypotonic solution means the solution has a higher water potential comparing the the cell.
In this case, the water molecules will move from the solution to the cell cytoplasm, due to the rule of osmosis.
Osmosis will always be the flow of water molecules from a region of higher water potential to a region of lower water potential, through a semi permeable membrane which is the cell membrane in this case.
In addition, if the cell is animal cell, it may burst since it gained so much water. But this won't happen in plant cells since it has a cell wall.