Answer:
1. Inhibiting IP3 channels, leading to decreased Ca2 in the sarcoplasm and reduced contraction.
2. Increasing the relative activity of MLCP, leading to a decrease in tension.
3. Activating K channels, increasing K leaking out of the cell which hyperpolarizes it and decreases the likelihood of Ca2 entry.
Explanation
In smooth muscle, cyclic AMP (cAMP) mediates relaxation because cAMP inhibits a specific kinase required for myosin light chain protein (MLCP) phosphorylation, thereby triggering contraction in the smooth muscles. It has been shown that cAMP inhibits 1,4,5-trisphosphate (IP3)-dependent calcium ions (Ca 2+) release by activation of the cGMP-dependent protein kinase (PKG). PKG proteins act to modulate Ca2+ oscillations by stimulating sarcoplasmic Ca2+-ATPase membrane proteins, increasing Ca2+ in the sarcoplasmic reticulum stores and Ca2+ efflux from the cells, and activate voltage-gated potassium (K) channels, thereby leading to membrane hyperpolarization and reducing Ca2+ entry through Ca2+ channels.
<span>Archaea are thought to have diverged from some ancient group of _______ bacteria<span><span><span> </span> gram-positive</span></span></span>
The flu vaccine is essential in our society and should be encouraged and financed whenever necessary. That's because, as we know, the flu is a disease of rapid proliferation and that imposes risks to the lives of some people. The vaccine has the ability to reduce the risk of a person being infected with the flu virus by 50%, this percentage is essential for people who are more sensitive to this virus such as the elderly, pregnant women and people with respiratory problems.
In addition, it is important that the manufacture and distribution of this vaccine is always financed, because the flu virus is a very changeable circle that is constantly changing and needs to be combated annually.
If we take the wolf as a species, then we can easily find its place and evolutionary path through this cladogram of chordates. The wolf is a vertebrate, so we start from vertebrae. It is an animal that has jaws and paired appendages. Continuing further up the cladogram we reach the development of lungs, and the wolfs have lungs for breathing. Then we come to the development of four limbs, and the wolfs have four limbs. Next comes the endothermy, meaning that the animal is able to regulate its own body temperature, thus it is warmblooded, and the wolfs are warmblooded animals. As last we come to the mammals, and the wolfs are part of the mammals, so we can classify them in that branch of the chordate cladogram.
I think it’s leaf okkkkkkkkkkkkkkkkkkkkkk
