The Nervous system releases dopamine and other reward chemicals in response to stimuli. Some such stimuli are addictive substances such as nicotine. When this happens the endocrine system sends bodily messages to relax. Having too much of an artificial substance provoking reward chemicals in your brain results in you not responding or producing enough on your own. Thus how addiction begins to occur. Hope this helps!
A lot of stores sell things in “bulk” like in grocery stores it’s more geared to families.
3,500 calories = 1 pound, so 3,500 would be the answer.
Damage to the brain because it could rot that one part of your brain