Answer: Missense mutation
Explanation:
Missense mutation is a type of point mutation where a single nucleotide is changed to cause substitution of a different amino acid. This in turns render the resulting protein non-functional.
In the case of sickle-cell disease, the sixth amino acid in the gene sequence, glutamate (GAG) is substituted with valine (GUA), due to Adenine nucleotide changed to Uracil nucleotide. Thus, missense mutation has occurred
Narcotics mimic the brain’s internal system....
