Answer:
About the induction of immunosuppressive therapy it is true that the goal of induction immunosuppression agent therapy is to significantly decrease the T cell response to the allograft (option C).
Explanation:
Immunosuppressive drug therapy is used when an organ transplant is performed, to prevent the transplanted organ from being rejected by the immune system.
One of the action mechanisms of immunosuppressors is to decrease the action of T lymphocytes, which are the main responsible for the rejection response to the transplant.
The function of T-lymphocytes can be:
- CD4⁺ are producers of antibodies, which can attack foreign tissue.
- CD8⁺ capable of directly attacking a transplanted tissue, recognized as foreign.
Drugs such as cyclosporine and tacrolimus prevent the activation of T-lymphocytes, preventing the rejection of transplanted organs.
the other options are not correct because:
<em> a. Immunosuppressive agents are not only administered before transplantation, but are used throughout life.</em>
<em> b. Immunosuppressive agents are not less powerful than therapeutic agents.</em>
<em> d. Immunosuppressants are not specific to prevent rejection of transplanted organs.</em>
