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He is saying to not judge a person before knowing them properly. To understand the perpectives of people that face things like discrimination and not to have bad opinions on them.
The famous "Out- Out" speech by Lady Macbeth in Act 5 Scene 1 ranks as one of the most performed Shakespearean sequences throughout the world. Part of the reason for this soliloquy's fame is how expertly Shakespeare interweaves lines from earlier in the play to present a woman sliding from guilt into madness.
