First pass metabolism of a drug is said to occur when the concentration of a drug that is administered orally is significantly reduced before it reaches the systemic circulation.
First pass metabolism usually occur in the liver.
The routes of drug administration that avoid complete first pass metabolism are: sublingual, transdermal, rectal and inhalation.
<span>A heterozygous individual is if a mutation occurs in just one copy of the gene.
If both copies of the gene are mutated than the individual is homozygous</span>
I think you're confused. There are only two sexes, male and female. Sex is what you were biologically born as from birth, while gender is what you choose to identify as. Gender is a choice, sex isn't. They couldn't discover any other genders because at the time they probably didn't even know what gender was like three thousand years ago, therefore they couldn't look like a different gender.
The significince about them as they think they came from the moon as i do mot know much about it you may be better by searching it up
the protist is eukaryotic
the protist is unicellular
the protist is a living organism