Decompression sickness manifests ITSELF with joint pain and it can be fatal.
'Itself is a word that is usually used as the object of a verb or preposition to refer to to an inanimate thing or an animal which has been mentioned previously as the subject of the sentence.
Murdered by two hired assassins
Making time to do your work and trying to get the right answers, studying and turning things in early or on time, making sure everything is complete