It shaped American foreign policy in the Middle East during his presidency.
Explanation:
9/11 caused the War in Afghanistan and made Bush declare a "war on terror". Conflicts part of the War on Terror would begin under his administration. For example, the Iraq War (which took up a good part of his presidency) is also considered part of the War on Terror. Overall, 9/11 and the War on Terror would make a foreign policy shaped around the idea of containing extremism during the Bush years.
The Black Death is believed to have been the result of plague, an infectious fever caused by the bacterium Yersinia pestis. The disease was likely transmitted from rodents to humans by the bite of infected fleas.