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VladimirAG [237]
4 years ago
5

Receptors are typically specialized to react to specific stimulation by initiating a ______ change.

Biology
1 answer:
DIA [1.3K]4 years ago
7 0
Receptors are typically specialized to react to specific stimulation by initiating a chemical or biochemical (in the case of biochemistry) change. In the field of pharmacology or biochemistry, receptors are usually a protein molecules and the change it undergoes are usually specific to the type of stimuli or signal it is responding to.
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Explain the process of mitosis in a tissue culture for cancer cells.
Tresset [83]

The cells divide and die at a relatively constant rate. Thus, the body permanently contains an identical number of cells. Everything is under the control of genes preventing uncontrolled proliferation.

However, they are sometimes victims of mutations and, in a certain context, the cells begin to multiply in an anarchic and uncontrolled way. It is the tumor, which can be benign (non-cancerous) or malignant (cancerous). Sometimes the body manages to get rid of it. Other times, unfortunately, this is not the case.

The cancer cell is an abnormal cell,

* which loses certain normal characters (Morphological and functional) and acquires

new specific characters that are transmitted to the child cells.

* and multiplies in an anarchic and autonomous way escaping the mechanisms of  regulation of cell division.

Cancer is characterized by a multiplication of cancer cells that divide by  mitosis. The number and the atypical character of the mitoses are in favor of the malignancy, One finds:

• Increase in the number of mitoses with shortening of the interphase.

• Abnormal, multipolar mitosis with irregular distribution of chromosomes.

It tends to expand (expansive character) in an unlimited way at the expense of the fabric in the  which it originated, but while maintaining a certain degree of differentiation related to its  original fabric.

6 0
3 years ago
Read 2 more answers
Identification of key microRNAs and the underlying molecular mechanism in spinal cord ischemia-reperfusion injury in rats
alexdok [17]

The underlying molecular processes for 19 important DE miRNAs in the etiology of SCII were confirmed. The DE miRNAs could serve as potential intervention targets for SCII. Additionally, blocking microRNAs-3568 reduced apoptosis and preserved hind limb function after SCII, possibly via modulating GATA6, GATA4, and RBPJ in SCII.

microRNAs:

  • Short non-coding RNAs called miRNAs (microRNAs) control post-transcriptional gene expression.
  • SCII (spinal cord ischemia-reperfusion damage) is a medical condition that can lead to paralysis and paraplegia, among other serious effects. The development of SCII is influenced by aberrant microRNAs expression. Different microRNAs expression results could be caused by variations in the experimenters, filtering circumstances, control choice, and sequencing platform.
  • The purpose of this study is to investigate the important differently expressed microRNAs (DE miRNAs) and the underlying molecular mechanism in SCII by methodically analyzing the available SCII microRNAs expression data. A thorough bioinformatics study of 23 representative rat SCII miRNA datasets from PubMed was carried out. On mi RDB, the target genes of important DE miRNAs were predicted.
  • Functional enrichment and transcription factor binding analyses using the DAVID and T Fact S databases. Nine were increased (miR-144-3p, miR-3568, miR-204, miR-30c, miR-34c-3p, miR-155-3p, miR-200b, miR-463, and miR-760-5p) and ten were downregulated (this study found 19 important DE miRNAs involved in SCII) (miR-28-5p, miR-21-5p, miR-702-3p, miR-291a-3p, miR-199a-3p, miR-352, miR-743b-3p, miR-125b-2-3p, miR-129-1-3p, and miR-136).Target genes of the increased DE miRNAs underwent KEGG enrichment analysis, which identified the pathways primarily involved as being the cGMP-PKG and cAMP signaling pathways. According to KEGG enrichment analysis of the downregulated DE miRNAs' target genes, the main signaling pathways involved were the Chemokine and MAPK signaling pathways. The target genes of the increased DE miRNAs were clearly enriched in biological processes such brain development and the positive control of transcription from RNA polymerase II promoter, according to GO enrichment analysis.
  • The majority of the target genes of the downregulated DE miRNAs were enriched in biological processes such intracellular signal transmission and the inhibition of cell growth. The transcription factor study revealed that the four transcription factors, SP1, GLI1, GLI2, and FOXO3, had significant regulatory effects on the main DE miRNAs' target genes. MiR-3568 stood out among the elevated DE miRNAs as being particularly intriguing. SCII results in significant neurological deficiencies in the lower extremities, but miR-3568 anti-miRNA oligonucleotides (AMOs) enhance neurological performance. When compared to the sham group, cleaved caspase-3 and Bax were significantly elevated in SCII, however the overexpression was inhibited by miR-3568 AMO. In contrast to cleaved caspase-3, Bcl-2 expression levels exhibited a pattern. Following the attenuation of this increase by SCII and microRNAs-3568 AMO, the expression of GATA6, GATA4, and RBPJ reduced.

Learn more about microRNAs here brainly.com/question/14979443

#SPJ4

8 0
2 years ago
How do some cells become brain cells and others become skin cells, when the DNA in all the cells is exactly the same?
SOVA2 [1]

Answer:

it has the ability to turn off genes

4 0
4 years ago
DNA is a type of<br> A. lipid<br> B. nucleic acid<br><br> C. starch<br> D. protein
timofeeve [1]
DNA is a nucleic acid, so B
6 0
3 years ago
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Which student can use their information to determine an atoms identity?
Ulleksa [173]
B.chan counts the number of protons
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3 years ago
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