<h3><u>Answer;</u></h3>
b). Activation of an upstream guanine nucleotide exchange factor
<h3><u>Explanation</u>;</h3>
- <em><u>When a ligand activates the G protein-coupled receptor, it induces a conformational change in the receptor that allows the receptor to function as a guanine nucleotide exchange factor (GEF) that exchanges GDP for GTPthus turning the G protein-coupled receptor on.</u></em>
- The activated G-protein then dissociates into an alpha (G-alpha) and a beta-gamma complex.
Answer:
the number of protons in an atom
The first two blanks are evidence of climate change, third blank is the main cause of climate change, and the fourth blank is a mechanism by which climate change occurs.
The sum of all the genes in a population is referred to as the gene pool.
Answer: Protein folding and oligomerization
Explanation:
Binding immunoglobulin protein (BiP) is a vital protein present in humans essential for the translocation of secreted peptides.
BiP is a molecular chaperone which is present in lumen of ER (endoplasmic reticulum) which binds to the new protein and then translocat into the ER. The protein in ER is maintained under subsequent condition and important for protein folding and oligomerization (conversion of a monomer or group of monomer into an oligomer).
Several other functions of BiP are:
- ER translocation
- ER-associated degradation (ERAD)
- UPR pathway
Hence, BiP is a chaperone, it is important for protein folding and oligomerization.
