It would make a good theme, you can never be perfect. Considering I have nothing to go off of, but, if someone were to strive for perfection it would go on and on for a long while. Until eventually the person realizes you can't be perfect, as there's no such thing. That would be the theme, and the reader would realize as well even if they work harder than nobody's worked before, you still cannot be perfect. Mistakes are always going to be made.
An example of a challenge facing the American people during the late 20th and early 21st century is public education. The American democracy depends on an educated and well informed citizenry.