Effects of Central Nervous System Depressants. Central nervous system depressants work by increasing the production of the neurotransmitter GABA, which in turn slows down brain activity and produces feelings of relaxation, drowsiness, and a number of other effects, including: Lowered blood pressure.
The formula to get the maximum heart rate calculation is 220 - age. So, if someone is 47 years old, their average max. heart rate would be 220 – 57 = 163
