In order for me to assist you, you must attach an image of the graph. :)
Water is used in many reactions in the body, both enzymatic and chemical. Water within blood and lymphatic system is responsible for the transport of hormones, antidotes oxygen and nutrients.
Metabolism can be described as entirety of chemical reactions which take place within a cell, the result of which is energy for processes which take place in the body.
The movement of air in the atmosphere. For example HOT air collides with COOL to get high winds and storms
We know that the Silurian period gave way to the Devonian period, which is when the Neogene era started, therefore:
The answer is B. before the Neogene era.
Hope it helped,
BioTeacher101