The answer is; Sodium (Na+) and Potassium (K+) Ions
These cations are pumped out of the cell by Na+-K+ transmembrane protein pumps leaving the inside of the cell electronegative in relation to the extracellular matrix. This membrane potential is significant especially for neurons. Depolarization of the membrane enables transmissions of an impulse along the neurons.
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No, because if their already formed, how would they get bigger
Answer:
By giving putting the patient under, giving the patient anesthesia.