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2 years ago

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Biology

1 answer:

allochka39001 [22]2 years ago

6 0

Answer:

A homogenous solution is uniform throughout. Meaning that it has the same composition/looks the same through out the solution. It can be called a homogenous solution or mixture. The other type of solution is a heterogenous solution. This solution is is visibly different looking, so it does not look the exact same throughout.

eg:

Milk is an example of a homogenous solution. It looks the same all throughout but when you look at it under a microscope you can then see it is actually consisted of different things.

Sand in a cup of water is a heterogenous solution. You are able to visibly see the different compounds that make up the solution.

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Answer:

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Explanation:

The Notch signaling pathway is a cell signaling system which consist basically of 4 NOTCH genes ( NOTCH1, NOTCH2, NOTCH3, and NOTCH4) each of them having the information to build a particular cell membrane receptor protein.

It has been demonstrated in zebrafish embryos that Notch signaling are highly determinant factors during vascular development, and a key function of these genes was specifically to regulate the differentiation of arterial fate in endothelial cells.

Notch signaling-deficient embryos showed a loss of expression of arterial markers such as ephrinB2 from arterial vessels with an accompanying expansion of venous markers into normally arterial domains. In contrast, embryos in which Notch signaling had been ectopically activated, meaning an activation out of "proper" place (where not expected, e.g. venous endothelial), exhibited the contrary phenotype, this is a suppression of vein-specific markers with ectopic expression of arterial markers in venous vessels.

To summarize, when Notch is supressed (in this case inhibited with a specific Notch inhibitor) arterial fate of endothelium is not followed, and venous fate is stablished. Thus, endothelial cells (those expected to form venous tissues but also arterial ones) would specified as venous.

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