Each gram of saturated fat give 9 calories. If Miguel's choice of the menu contained 6 gram of saturated fat,he choice contained 6g*9cal/g=54cal.
Miguel's choice had a total of 460 calories. 54 calories of saturated fat is equivalent to (54cal*100%)/460cal=11.74%.
The percentage of calories from saturated fat is 11.74.
Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Answer:
Mitochondria.
Explanation:
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which the neuron died due to mutation in superoxide dismutase 1 gene. This disease is also known as Lou Gehrig's disease.
Mitochondria structure is disorganized in ALS. The ubiquitin protein mutation leads to the malfunctioning of mitochondria and misfolded proteins are made in the mitochondria.
Thus, the correct answer is option (a).
