Explanation:
In biology, hyperpolarization is any change in the cell's membrane potential, which makes it more polarized. That is, hyperpolarization is an increase in the absolute value of the cell's membrane potential. Thus, changes in the membrane voltage in which the membrane potential is more clearly positive or negative, are hyperpolarizations.
An enzyme is a substance produced by a living organism that acts as a catalyst to bring about a specific biochemical reaction. nucleus.
The answer is the second one: an underactive pituitary gland