Question

Which observation would most seriously challenge the hypothesis that most noncoding DNA is slightly deleterious?

Answer 1

Answer:

Species with larger population sizes have more noncoding DNA.

Explanation:

The statement that most non-coding DNA is deleterious contradicts the fact that Species with larger population sizes have more noncoding DNA. Had the non coding been deleterious , its proportion in species with larger population would have been less but the fact that species with larger population sizes have more noncoding DNA contradicts it.