The answer would be:<span> Dosage may need to be decreased.</span>
Dobutamine is a drug that increases the strength and frequency of heart pump. It is frequently used in ICU to help the patient with a heart problem. While it can help strengthen the heart, high doses might cause arrhythmia which could threaten the patient life. That is why the doses need to be titrated carefully.
<span>Moderate </span>alcohol<span> intake doesn't </span>kill brain cells<span>, or even </span>damage<span> them. That's because the amount of </span>alcohol<span> needed to </span>kill brain cells would<span> also </span>kill<span> the person </span>drinking<span> it. That doesn't </span>mean<span> that </span>alcohol can<span>'t </span>damage<span> the </span>brain <span>though.</span>
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Substrate concentration affect enzyme activity -
1. There is more enzyme activity at higher substrate concentrations due to more collisions between enzyme and substrate until a maximum rate is reached
2 Once the maximum reaction rate for the enzyme is reached, the reaction rate levels off.
The enzymatic reaction depends on various factors including temperature, substrate concentration, concentration enzyme, and other factors. The rate of a chemical reaction is affected by the total number of enzymes as well as the concentration of substrate
- Increasing substrate concentration increases the activity of a corresponding enzyme
- After a certain point, the rate of activity will cease to rise regardless of any further increases in substrate levels as the environment is saturated with substrate and all enzymes are bound and reacting to the maximum limit.
- A high concentration of substrate causes increases in a collision between enzyme and substrate.
- Collisions bring substrate molecules and enzymes together and increase enzymatic activity.
Thus, Substrate concentration affect enzyme activity -
1. There is more enzyme activity at higher substrate concentrations due to more collisions between enzyme and substrate until a maximum rate is reached
2 Once the maximum reaction rate for the enzyme is reached, the reaction rate levels off.
Learn more about Enzymes:
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