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Consider transfusion if hemoglobin is 8 g/dL or below or if there are symptoms (chest pain, orthostatic hypotension or tachycardia unresponsive to fluid resuscitation, or congestive heart failure).
For inpatients with active acute coronary syndromes and a Hb level less than 8 g/dL, transfusion should be taken into consideration. Adult critical care medical and surgical inpatients with an Hb level less than 10 g/dL may receive a transfusion while receiving sepsis treatment within the first six hours of resuscitation. Acute sickle cell crisis, acute blood loss of more than 30% of blood volume, and symptomatic anemia (which results in shortness of breath, fainting, congestive heart failure, and decreased exercise tolerance) are all indications for transfusion.
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Answer:
1.) Abnormal parameters:
- Difficulty focusing (confusion)
- Elevated heart rate (tachycardia), with thready and weak pulse quality
- Elevated respiratory rate (tachypnea). Rapid and shallow respiration.
- Low blood pressure (hypotension)
- Low blood glucose (hypoglycemia)
- Low serum sodium (hyponatremia)
- High serum potassium (hyperkalemia)
- High ACTH
- Low cortisol (hypocortisolism) (Note: this lab values are obtained normally at 8am, due to its physiological curve)
2.) Addison’s disease
- Confusion: Hyponatremia causes confusion, due to neuronal imbalance.
- Tachycardia: Inmediate response to hypotension, so as to maintain a adequate cardiac output.
- Tachypnea: Hyperkalemia produces an acid-base imbalance (acidemia), which normally can be compensated by changes in the respiratory rate.
- Hypotension: hyponatremia produces reduced water retention in blood vessels, affecting blood pressure
- Hypoglycemia: hypocortisolism directly affects blood glucose (decreased gluconeogenesis)
- Hyponatremia: Sodium retention will be reduced due to the absence of Aldosterone,
- Hyperkalemia: Potassium excretion will be reduced due to the absence of Aldosterone.
- High ACTH: No negative feedback inhibits the production of ACTH (depends on cortisol level).
- Hypocortisolism: Due to the non functioning cortex of adrenal gland, no cortisol is being produced.
Explanation:
Addison’s disease, also known as adrenal insufficiency, is a set of characteristic signs and symptom caused by the failure of the adrenal gland to produce steroid hormones, mainly Cortisol and in some cases Aldosterone. This syndrome presents various causes, incluiding autoinmune disease, infectious, and infiltration by cancerous cells.
Answer:
True
Explanation:
It is always good to be knowledgeable on any subject, especially for potentially harmful substances.