Rome's location on the Italian peninsula, and the Tiber River, provided access to trade routes on the Mediterranean Sea. As a result, trade was an important part of life in ancient Rome. ... Later, the Roman armies used these same routes to conquer large amounts of territory and expand the empire along the Mediterranean.
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ANSWER: Indus Valley
Many historians believe the Indus civilization collapsed because of changes to the geography, climate of the area, halted trade with Mesopotamia, and Aryan invasions.
The impact of this Age of Exploration to China is Economic Imperialism for foreign explorers.
The middle Kingdom of China was unstable during that time and was too weak to defend its vast lands, and China has highly rich resources that are needed in manufactures. It made China an attractive place for commerce.
Besides this, China has routes that are convenient passages for ships. Other trade like opium also took place between China and Britain, it made people stay in some places and use drugs all day.
One good impact in China with trading are things it learned to improve their ship designs after seeing the ships of the western explorers.