A group of Chinese women with PCOS who were receiving treatment saw several metabolic and hormonal imbalances improve after taking BBR. The primary consequences may be connected to the modifications in body composition in obesity and dyslipidemia. For the evaluation of the possible beneficial metabolic effects of BBR in women with PCOS, additional controlled trials are required.
PCOS:
- Objective: Insulin resistance is a common metabolic and reproductive condition called polycystic ovarian syndrome (PCOS) (IR). A quinoline derivative alkaloid known as berberine (BBR) has been utilized as an insulin sensitizer and is isolated from Chinese medicinal herbs. There may be a therapeutic benefit for PCOS from BBR. The purpose of this study was to compare the effects of BBR and metformin (MET) on the metabolic characteristics of PCOS-affected women.
- Design and methods: Ninety nine PCOS and IR patients were randomly assigned to one of three therapy groups: BBR+ compound cyproterone acetate (CPA;
), MET
CPA
, and placebo CPA 
for 
months. Before and after the treatment period, metabolic and hormonal measures as well as the clinical characteristics of the women were evaluated. - Results: Reduced waist circumference, waist-to-hip ratio (WHR;P<
), total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDLC; P<
), as well as increased levels of high-density lipoprotein cholesterol (HDLC) and sex hormone-binding globulin (SHBG; P<) were all observed following treatment with BBR as compared to MET. Similarly, BBR treatment decreased WHR, fasting plasma glucose, fasting insulin, homeostasis model evaluation for IR, area under the insulin curve, TC, LDLC, and TG (P<), while increasing HDLC and SHBG (P<) as compared to placebo.
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when the see levels rises the great barrier reef will have less and less fishes
Structure and Function is my answer
The cells that produce pepsin, an enzyme that breaks down proteins during the digestive process is Chief cells. Pepsin is the main digestive enzyme in the stomach that breaks down proteins. Pepsin is produced by the chief cells in the inactive form pepsinogen, which is then converted to pepsin by the hydrochloric acid from the parietal cells.
Answer:B6 and B12.
Explanation:
Homocysteine is an amino acid produced from demethylation of methionine.The later is an amino acid needed in the body which must be conserved.
In order to conserve it ,Homocysteine is recycled in a specific pathways which inovles activities of Vitamin B6 and B12
.Therefore deficiency of these vitamins leads to elevated levels of Homocysteine.
HIGH LEVELS OF HOMOCYSTEINE AFFECT THE ENDOTHELIAL CELLS ;LEADING TO ABNORMAL CLOTTING OF BLOOD.THIS INCREASE IN BLOOD VISCOSITY PUT THE HEART AT RISK OF CARDIOVASCULAR DISEASES.
