OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
Here is an idea
You can either tell the importance of sports why sports is important and do a conversation between four people like two of the people are lazy and you and you and your friend tell them about sport activities and sport centres there importance and how we can do them in daily life.
<span>(Part A) Inglis admires her family members who fight against apartheid because of the risks they take.
</span><span>(Part B) Inglis lists examples of how her family suffers, including her sister’s imprisonment and her brother's need to hide from the authorities.
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The moral of Guy de Maupassant’s “The False Gems” (“Les Bijoux” in French, 1883) sharply questions the hypocrisy of its male protagonist, Monsieur Lantin. Lantin is passionately in love with his young wife, whom he sees as the embodiment of beauty and virtue. His wife is perfect in every aspect, except for her love of imitation jewelry and the theater. Being of a puritanical bent of mind, Lantin finds both of his wife’s interests showy and improper. Clearly, such interests do not fit his worldview of what a well-brought-up, modest woman should be enjoying. At one point he remonstrates her ostentatious tastes, saying:
My dear, as you cannot afford to buy real diamonds, you ought to appear adorned with your beauty and modesty alone, which are the rarest ornaments of your sex.
Clearly, it is not the fact that she wears jewelry which bothers Lantin, but the fact that these gems are false. Despite having such fixed notions about real and fake, truth and deception, Lantin is ironically oblivious to how his wife manages to eke out their lavish lifestyle on his modest salary of 3,500 francs. After his wife dies of a lung infection, Lantin is heartbroken. But soon the heartbreak is replaced by financial hardship: left to manage his income by himself, Lantin struggles for even his next meal. Here, he commits his first act of impropriety, attempting to sell off his beloved wife’s imitation jewelry. Thus, the text begins to reveal his hypocrisy.
When a jeweler’s appraisal shockingly reveals that the ornaments are not fake at all, but real and precious, Lantin’s hypocrisy sparkles as well. At first, he falls into a “dead faint” at the implication of the jewelry's actual worth. His modest, virtuous wife was clearly leading a double life, being gifted gems from her many admirers. It was this double life that funded the extravagant lifestyle of the Lantins.
But Lantin’s state of shock at his wife’s “betrayal” does not last long and gives way to something else quickly enough. Instead of shunning the income, which should be deemed dubious by his strict standards, he sells off all the jewelry, resigns from his job, and settles into a life of leisure. In this, the story exposes Lantin’s hypocrisy completely. His love for his wife perishes with her “deception,” but he is not above enjoying the fruits of her lies. He even discovers a love for the theater, for which he harshly judged his late wife. And soon enough he remarries, but in a cunning twist, the effect is not what he had hoped.
Six months afterward he married again. His second wife was a very virtuous woman, with a violent temper. She caused him much sorrow.
As we see, the story challenges Lantin’s definitions of truth, happiness, and virtue in a wife; and he gets his just desserts for his double standards. The wife he considered “impure” was the one he was truly happy with, while the truly virtuous woman causes him “much sorrow,” as he deserves.
