1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
JulsSmile [24]
3 years ago
11

Leigh's disease is a mitochondrially inherited disease with symptoms that include seizures, fatigue, impaired reflexes, breathin

g problems, and ataxia. The pedigree shows the presence of Leigh's disease in three generations. Individual 4 had two daughters and one son, and individual 6 had one daughter and two sons. Which of the individuals indicated are affected by Leigh's disease
Biology
1 answer:
Ahat [919]3 years ago
5 0

About the question:

You will find the pedigree in the attached files

Answer:

  • individual 4 → Affected woman → Black circle
  • individual 5 → Affected woman or man → Black circle or square
  • individual 7 → Healthy woman → Empty circle
  • individual 10 → Affected boy → Black Square

Explanation:      

Mitochondrial inheritance is the transmission of a disease or a trait from the maternal line.

<em>Most of the DNI is in the nucleus, but there is also DNI in mitochondria. Sperm cells hardly transfer mitochondrial genes to the progeny</em>, so mitochondrial DNI is mostly inherited from the maternal side. If there exists any mutation in this mitochondrial DNI, the whole progeny of the mutated woman will be affected, as they will get the mother genotype carrying the mutation. On the contrary, if an affected man is carrying a mutation in mitochondrial DNI, non of their descendants will get the disease.

Before answering the question, let us remember the pedigree symbols.

  • Squares represent Males/Men
  • Circles represent Females/Women
  • Empty symbols represent healthy/non-affected individuals
  • Solid black symbols represent sick/affected individuals

In the exposed pedigree, we can see that the mother is affected by the disease (individual number 2), so all her children are also affected (individuals 4, 5, and 6) because the <em>disease is mitochondrially inherited</em>.

Individual 3 is a healthy man, so individual 4 must be an affected woman (Black circle). As she is the one affected, then all her children will also be affected. This couple <em>had one boy and two girls</em>. Individuals 8 and 9 are girls (circle), so individual 10 must be the affected boy (black square).  

On the other hand, individual 6 is an affected man (black square), son of individuals 1 and 2. This man couples with a woman, and they have all healthy children. So this woman (individual 7) must be healthy. Even though the man is affected, all their children are not because their mother (7) is not. Remember that sperm cells do not transmit the mitochondrial genes to the progeny.      

And finally, individual number 5 might be either a man or a woman. In any case, this person is also affected by Leigh's disease.  

You might be interested in
How many amino acids can a sequence of 24 DNA bases code for?
timurjin [86]
The answer your looking for is 20 Amino Acids.<span>
</span>
6 0
3 years ago
Which one is it??<br> It’s on usatestprep.
sweet-ann [11.9K]

The other guy is right, B is the answer now hurry and get that test prep done

8 0
3 years ago
Allosteric proteins and the regulation of metabolic pathways would be expected to be found at ________ and ____________ of metab
scoundrel [369]

Answer:

e) B and C

Explanation:

Allosteric regulation occurs at these points where the concentration of the substrate and/or products is important for the activation and inhibition of the enzyme.

3 0
3 years ago
Which of the following is a characteristic of a scientific theory? (5 points) It explains how nature works. It is based on a sin
KIM [24]

Answer:

<em> It explains how nature works.</em>

Explanation:

A scientific theory can be described as a descriptive explanation of the occurrence of any phenomenon taking place in the natural world. Other statements are not true because a scientific theory is explained best with the help of certain experiments and certain known facts. It might be based on results from many experiments and supported through many known facts. A scientific theory has the capacity to replicate its results when performed again and again.

3 0
3 years ago
Read 2 more answers
What are the three stages of photosynthesis ​
AnnZ [28]

Absorption of light electron transport leaning to the reduction generation of ATP and conversion of CO2 into carbohydrate

3 0
3 years ago
Other questions:
  • What are the consequences to utilizing DNA technology in forensics? Check all that apply.
    9·2 answers
  • Master genes that affect development tend to be highly ____; therefore, similarities in patterns of embryonic development reflec
    5·1 answer
  • What are the abiotic elements of the ocean? :) :) :) :)
    8·2 answers
  • Archaea are thought to have diverged from some ancient group of _______ bacteria.
    6·2 answers
  • Identify the following sample.
    12·2 answers
  • What does NASA like to call the free-fall condition while on the space station?
    7·2 answers
  • Causes water molecules to rise up from the roots eventually reaching the leaves?
    15·1 answer
  • Which Behavior is a Response to an External Stimuli?
    11·1 answer
  • In which areas are earthquakes more likely to occur? Select one: O Polar regions O Island shorelines. O Within 10 miles of activ
    14·2 answers
  • The part of earth that contains all life all ecosystems including land water and air/atmosphere
    8·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!