1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
JulsSmile [24]
3 years ago
11

Leigh's disease is a mitochondrially inherited disease with symptoms that include seizures, fatigue, impaired reflexes, breathin

g problems, and ataxia. The pedigree shows the presence of Leigh's disease in three generations. Individual 4 had two daughters and one son, and individual 6 had one daughter and two sons. Which of the individuals indicated are affected by Leigh's disease
Biology
1 answer:
Ahat [919]3 years ago
5 0

About the question:

You will find the pedigree in the attached files

Answer:

  • individual 4 → Affected woman → Black circle
  • individual 5 → Affected woman or man → Black circle or square
  • individual 7 → Healthy woman → Empty circle
  • individual 10 → Affected boy → Black Square

Explanation:      

Mitochondrial inheritance is the transmission of a disease or a trait from the maternal line.

<em>Most of the DNI is in the nucleus, but there is also DNI in mitochondria. Sperm cells hardly transfer mitochondrial genes to the progeny</em>, so mitochondrial DNI is mostly inherited from the maternal side. If there exists any mutation in this mitochondrial DNI, the whole progeny of the mutated woman will be affected, as they will get the mother genotype carrying the mutation. On the contrary, if an affected man is carrying a mutation in mitochondrial DNI, non of their descendants will get the disease.

Before answering the question, let us remember the pedigree symbols.

  • Squares represent Males/Men
  • Circles represent Females/Women
  • Empty symbols represent healthy/non-affected individuals
  • Solid black symbols represent sick/affected individuals

In the exposed pedigree, we can see that the mother is affected by the disease (individual number 2), so all her children are also affected (individuals 4, 5, and 6) because the <em>disease is mitochondrially inherited</em>.

Individual 3 is a healthy man, so individual 4 must be an affected woman (Black circle). As she is the one affected, then all her children will also be affected. This couple <em>had one boy and two girls</em>. Individuals 8 and 9 are girls (circle), so individual 10 must be the affected boy (black square).  

On the other hand, individual 6 is an affected man (black square), son of individuals 1 and 2. This man couples with a woman, and they have all healthy children. So this woman (individual 7) must be healthy. Even though the man is affected, all their children are not because their mother (7) is not. Remember that sperm cells do not transmit the mitochondrial genes to the progeny.      

And finally, individual number 5 might be either a man or a woman. In any case, this person is also affected by Leigh's disease.  

You might be interested in
Give an example ecological disturbance. Light Disturbance? Extreme Disturbance.
nalin [4]

Answer:

In contrast, major disturbances include large-scale wind events (such as tropical cyclones), volcanic eruptions, tsunamis, intense forest fires, epidemics, ocean temperature changes stemming from El Niño events or other climate phenomena, and pollution and land-use conversion caused by humans.

Explanation:

3 0
2 years ago
If predators A and B prey upon the same species and predator A is eliminated, the population of predator B will likely _________
Allushta [10]

Answer:

Increase

Explanation:

The predator is a type of animal or bird species which kill other animals to obtain its food. The prey is the animal which is killed by the predator. According to the given situation, if the predator species A is eliminated, the population of the predator B will likely increase because there will be no competition between the two species for the same prey. And the chances of predator B obtaining the prey will increase. Hence, the population will increase.

4 0
3 years ago
Read 2 more answers
A plant cell has lost too much water due to evaporation by the sun. It needs more water from other cells. What structure would a
Maru [420]
Normally it’s the plasmodesmata that allows exchange of molecules between adjacent cells. But I’m still not sure if water is included!
3 0
3 years ago
Read 2 more answers
Division of labour is not found in
docker41 [41]

Answer:water

Explanation:

4 0
2 years ago
Anyone know how to awnser the bottom portions?
Vedmedyk [2.9K]
Hypothesis: If plants are placed in white light, then the will grow better than plants in other colours of light.

Independent variable: Colour of light.

Dependent variable: plant growth.

Control group: the plant in the closet.

Experimental group: the plant is the other light colours.

Constants: miracle grow and amount of water.

Measurements: height of plants.
6 0
3 years ago
Other questions:
  • What leads to the formation of a windchill factor?
    6·2 answers
  • Scientists discovered bacteria for the first time in the 1920s true or false
    14·2 answers
  • What is the outcome when a cell undergoes meiosis
    8·2 answers
  • List the 3 Terrestrial Consumers that are Herbivores:<br> 1.<br> 2.<br> 3.
    13·1 answer
  • Intestinal worms, like tape worms, are parasites that are too large for phagocytosis. Therefore, they are weakened and destroyed
    14·1 answer
  • Name the phenomenon that results when a red flower plant is crossed with a white flowered plant and the offspring have pink flow
    7·1 answer
  • Due to _____ memory, people are able to recover from being distracted or not paying attention when someone is speaking by relyin
    13·1 answer
  • What are some personal thoughts on air pollution.
    12·1 answer
  • All living things have DNA? true or false
    11·2 answers
  • a cell contains a 4% concentration of salt. the cells enviornment is isotonic. which is a possible salt concentration outside th
    7·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!