1.) A nucleotide of DNA consists of a sugar, a phosphate, and a nitrogen containing base.
2.) A mutation is a change in the base sequence of a DNA molecule
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Conventional genetic analyses of rRNA sequence is not possible for prions because they don't contain nucleic acid.Prions do not contain genetic material such as - DNA and RNA.
The unique traits and genetic material information are encoded with the conformation structure and modification of protein.Prions which are responsible for transmissible sponginess encephalitis is mammals which all known prion disease affect the neural tissues.
There are 253 amino acids exist in multiple conformations and isoform which is found in healthy organisms, most extensively studied proteins. Prions are not destroy easily and remains intact in the presence of radiation , disinfectant and extreme heat.
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