Sacagawea had a major impact on the expedition of Lewis and Clark because she served as an important guide and interpreter in their exploration of the western United States. This expedition took place between 1804 to 1806 and they traversed thousands of miles from North Dakota to the Pacific Ocean.
Not positive, but I believe the answer is A because the wsr of 2812 was also known as the French and Indian war. If this is for a grade, do not use this answer unless you know it is correct.
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Explanation: the answer is a
Started in the 18th century