The answer is a. Pleistocene.
A group of large animals that lived during the Pleistocene is called Pleistocene megafauna. This group included mammoths, giant sloths, mastodons, cave bears, saber-toothed cats, etc. The extinction of these animals happened also in Pleistocene. The reasons for their extinction could be hunting by the humans, climate changes, or impact of asteroides.
D because just because of all the other effects it has no salt effect on the ocean
C ; The are most active at temperatures about 53 degrees
The sub units that make up Macromolecules are proteins, lipids, nucleic acids, and carbohydrates.