Boone is most famous for his exploration and settlement of what is now Kentucky, which was then part of Virginia but on the other side of the mountains from the settled areas.
Answer:
Gas Poisoning
Explanation:
World War I marked one of the biggest jumps forward for weapons of death and destruction. Many who came back were affected for the rest of their lives by the mustard gas that they were exposed to in the trenches of France.
Russia
It may sound dumb I don't really know at this point anymore
Trade across the Sahara became possible and it impacted West African empires by influencing them on a cultural level. The peak of Saharan trade extended from the 8th century until the early 17th century.