Answer: A mutation Changes by its mistake in the DNA which results in the wrong amino acid being incorporated into a protein because of change, that single DNA sequence change, results in a different amino acid codon which the ribosome recognizes.
Explanation:
A mutation changes the instructions of a gene, which can also change the protein. Sometimes this change makes it so the protein can't do its job as well. And this is what happens with sickle cell anemia. A mutation in the hemoglobin gene changes the hemoglobin protein in a way that causes sickle cell anemia.