DNA has unique properties that allow it to accurately retain genetic information, even after multiple rounds of replication. One aspect of DNA that allows it to accurately store genetic information is the base pairing from Chargaff's first rule of the four nucleotide bases. If the A content of a DNA molecule is 22%, what are the percentages of the remaining bases?
Answer:
T= 22%
G= 28%
C=28%
Explanation:
With the help of Chargaff's rule, the percentage of each of the four types of nucleotide bases in a double-stranded DNA can be calculated. It is based on complementary base pairing rule which in turn makes the percentage of adenine bases equal to that of the thymine bases in a double-stranded DNA. Similarly, percentage of guanine and cytosine bases in a DNA duplex is equal since G always pairs with C. Therefore, if a DNA duplex has 22% adenine nucleotides, percentage of thymine bases would be= 22%
Total percentage of A and T bases in the given DNA= 22 + 22 = 44%
Total percentage of G and C bases = 100-44= 56%
Percentage of G and C bases each= 56/2= 28%
