As a scientist employed by the FDA, you've been asked to sit on a panel to evaluate a pharmaceutical company's application for a
pproval of a new weight loss drug called Fat Away. The company has submitted a report summarizing the results of their animal and human testing. In the report, it was noted that Fat Away works by affecting the electron transport chain. It decreases the synthesis of ATP by making the mitochondrial membrane permeable to H+, which allows H+ to leak from the intermembrane space to the mitochondrial matrix. This effect leads to weight loss.How would you explain the decreased synthesis of ATP?
Whilst also growing the basal leakage of protons, this same drug Fat blocks the development of ATP. The whole change throughout the electrochemical gradient including its proton, therefore, induces the release of a possible form of radiation, rather than being transferred to ATP.
Through thermoregulatory autophagy, outlet temperature throughout the individual contributes to loss, associated with elevated body temperature. Elevated body temperature would have the additional effect of removing fat.
