Yes, it is true that Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia.
Focal malformations of cortical development, including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), are important causes of intractable childhood epilepsy.
Using targeted and exome sequencing on DNA from resected brain samples and non-brain samples from 53 patients with FCD or HME, we identified pathogenic germline and mosaic mutations in multiple PI3K/AKT pathway genes in 9 patients, and a likely pathogenic variant in 1 additional patient.
Our data confirm the association of DEPDC5 with sporadic FCD but also implicate this gene for the first time in HME. Our findings suggest that modulation of the mammalian target of rapamycin pathway may hold promise for malformation-associated epilepsy.
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The magnetic field of a bar magnet is the strongest at either pole of the magnet. It is equally strong at the North Pole when compared with the south pole. So I would say the answer is A.
Glucose is consumed and carbon dioxide is produced during the combined processes of glycolysis and cellular respiration.
Glucose is a simple sugar. Glucose is the most common monosaccharide, a type of carbohydrate. Glucose is primarily produced by plants and most algae during photosynthesis from water and carbon dioxide with the help of sunlight, where it is used to produce cellulose in cell walls, the world's most abundant carbohydrate.
A glucose molecule is gradually broken down into carbon dioxide and water during cellular respiration. Some ATP is produced directly along the way in the reactions that transform glucose. However, much more ATP is produced later in the process known as oxidative phosphorylation. The movement of electrons through the electron transport chain, a series of proteins embedded in the inner membrane of the mitochondrion, drives oxidative phosphorylation.
During glycolysis, a six-carbon sugar, glucose, undergoes a series of chemical transformations. It eventually degrades into two molecules of pyruvate, a three-carbon organic molecule. ATP is produced in these reactions.
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Answer:
Filtration, Reabsorption, Secretion: The Three Steps of Urine Formation. The kidneys filter unwanted substances from the blood and produce urine to excrete them. There are three main steps of urine formation: glomerular filtration, reabsorption, and secretion.
Explanation:
Sit in front of a heater- what are the options
