Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
There is only one measure of "evolutionary success": having more offspring. A "useful" trait gets conserved and propagated by the simple virtue of there being more next-generation individuals carrying it and particular genetic feature "encoding" it. That's all there is to it.
One can view this as genes "wishing" to create phenotypic features that would propagate them (as in "Selfish Gene"), or as competition between individuals, or groups, or populations. But those are all metaphors making it easier to understand the same underlying phenomenon: random change and environmental pressure which makes the carrier more or less successful at reproduction.
You will sometimes hear the term "evolutionary successful species" applied to one that spread out of its original niche, or "evolutionary successful adaptation" for one that spread quickly through population (like us or our lactase persistence mutation), but, again, that's the same thing.
They can use those recently discovered genes and insert them in another species (fruits and vegetables) using genetic ingeniery technics so they can speed up the cell division on them, and accordingly increase the production.
Answer:
There is an outer core and an inner core. The outer core is extremely hot and is made mostly of molten (or melted) iron, which is called magma. It is about 1300 miles thick
