The most significant limitation to the clinical utility of anthracycline antineoplastic medicines, which include doxorubicin (adriamycin), daunorubicin, or epirubicin, is the danger of cardiotoxicity.
- Nevertheless, these substances continue to rank among the most popular anticancer medications.
- Although the oxidative stress-based concept involving intramyocardial formation of reactive oxygen species (ROS) has acquired the most respect, the molecular etiology of anthracycline cardiotoxicity is still quite debatable.
- Through redox cycling of both their aglycones and anthracycline-iron complexes, anthracyclines may facilitate the generation of ROS.
- Given the remarkable cardioprotective efficacy of dexrazoxane, this suggested mechanism has gained a lot of traction (ICRF-187).
What is Influenza?
- It affects the lungs, nose, and throat.
- High-risk groups include young children, elderly individuals, pregnant women, persons with chronic illnesses, and those with weakened immune systems.
- Fever, chills, muscle pains, cough, congestion, runny nose, headaches, and exhaustion are some of the symptoms.
- Rest and fluids are the main treatments for the flu because they allow the body to fight the illness on its own.
- Anti-inflammatory painkillers sold over-the-counter may aid with symptoms. An yearly flu shot can lessen complications and aid in prevention.
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1. SI,
2. Number 10.
I'm pretty sure it's that, I just did something related to that.
Early hypothesis was not based on experimentation
