Number 5 would be the best awnser.
As a scientist who remains impartial can more accurately conclude his data while doing experiments.
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
The correct answer is "C."
mRNA stands for messenger Ribonucleic acid. The role of mRNA is to carry genetic information for the synthesis of protein from the nucleus after transcription.
After the transcription process is over, the mRNA leaves the nucleus and heads to the ribosomes in the cytoplasm where translation of this information takes place.
The ribosomes are the work bench of the cell. They receive the mRNA with its coded information, read it and translate it and with the help of tRNA (transfer RNA), amino acids are fetched from the cytoplasm and linked together to form the exact protein that was coded for on the mRNA.
Answer:
I do that sometimes I take notes in a separate location so is this like for your math homework cuz I am good enough but I don't like it that much but I'm good at it and sources identify things that will the source is like a key a key like you can open and close the door with and you're opening the key with the source so it really really really really and wouldn't be a good thing to take notes wherever you go like if you were writing a book you would want the source and the emotion and everything you wanted to buy
