All the options are correct.
As we know before Missouri Compromise of 1820, there were 11 free states and 11 save states and so there was a balance of power between North and South. The admission of Missouri as a slave state would result the imbalance. So we see Henry Clay, a congressman came with Missouri Compromise which provided for admission of Missouri as a slave state along with Maine as a free state in order to maintain the balance of power. It also prohibited slavery in the north of 36*30 parallel, excluding Missouri. So ultimately resolved the heated issue of the time in the Senate over slave states and free states. As it was a controversial act, it was later declared unconstitutional and was repealed by Kansas-Nebraska Act of 1854.
- He sought a Northwestern route across the continent to the Pacific Ocean.
- He hoped to persuade Native American groups in the Lower Mississippi Valley to cede their lands in exchange for land in the Louisiana Territory.