In the broadest sense of the term, we have modified the genes of almost everything. We used selective breeding to breed the most resistant form of crops, the largest sized chickens, and others. In recent years we have even modified them through gene splicing and other methods. Nearly everything we eat, including including "organic" foods have been changed from their original DNA structure, in fact we do not even know anything's original genetic structure because of this. Genetic modification could also include mutations. Some crops have mutated due to pollution, disease, or other effects such as climate change. Without genetic modification our world would differ from what it looks like today.
Super heated liquid molten lava
Anti-codon is complementary to the MRNA Codon
The gravitional force that the earth has on the moon would be less because the distance increased