You didn't include the map, so I can't be entirely sure, but if it's the same test that I have, it's B.
I think Rome to Athens is incorrect. According to my research, Massilia to Carthage is the route that involves trade outside of the Byzantine Empire.The Byzantine Empire was also known as the Eastern Roman Empire. Its capital city was Constantinople. The routes Rome to Athens, Alexandra to Ravenna and Antioch to Ephesus all fall within the Byzantine Empire. The Byzantine Empire was the most powerful empire during its existence and survive the breaking up and fall of the Western Roman Empire.
The answer could be that how his family and White House mislead the public about his illness. James Reston comments that journalists do not take the health of candidates seriously and that needs to change.
B. an elected school board