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The normal blood pH for adult humans is 7.40, and this pH value is vigorously defended at normal body temperature
Acid base Homeostasis is the method by which body keeps a constant ph
pH is kept under check via different systems
1. Chemical system :bicarbonate buffer system(explained below )
Respiratory component :
2. Respiratory Component: The second line of dense is rapid consisting of the control the carbonic acid concentration in the ECF by changing the rate and depth of breathing by hyperventilation or hypoventilation. This blows off or retains carbon dioxide (and thus carbonic acid) in the blood plasma as required
3.Metabolic component : third line of defense is slow, best measured by the base excess,eand mostly depends on the renal system which can add or remove bicarbonate ions to or from the ECF.Bicarbonate ions are derived from metabolic carbon dioxide which is enzymatically converted to carbonic acid in the renal tubular cells.There, carbonic acid spontaneously dissociates into hydrogen ions and bicarbonate ions.When the pH in the ECF falls, hydrogen ions are excreted into urine, while bicarbonate ions are secreted into blood plasma, causing the plasma pH to rise.The converse happens if the pH in the ECF tends to rise: bicarbonate ions are then excreted into the urine and hydrogen ions into the blood plasma.
Buffers usually consist of a weak acid and its conjugate base; this enables them to readily absorb excess H+ or OH–, keeping the system’s pH within a narrow range.
Maintaining a constant blood pH is critical to a person’s well-being. The buffer that maintains the pH of human blood involves carbonic acid (H2CO3), bicarbonate ion (HCO3–), and carbon dioxide (CO2). When bicarbonate ions combine with free hydrogen ions and become carbonic acid, hydrogen ions are removed, moderating pH changes. Similarly, excess carbonic acid can be converted into carbon dioxide gas and exhaled through the lungs; this prevents too many free hydrogen ions from building up in the blood and dangerously reducing its pH; likewise, if too much OH– is introduced into the system, carbonic acid will combine with it to create bicarbonate, lowering the pH.
Example: Antacids, which combat excess stomach acid, are another example of buffers.
ECF =Extra cellular fluid
Answer:
CCAGGCC
CCATCGA
GGCCATC
CAT
AGGCCAT
CATCGAG
Explanation:
Shotgun sequencing is a method used to determine the nucleotide sequence of entire chromosomes/genomes. This sequencing method consists of obtaining random DNA fragments which are subsequently classified by bioinformatic tools that ordering them according to overlapping sequences called contigs. In the whole-genome shotgun (WGS) technique, the entire genome of an organism is sequenced, being the critical factor the depth of sequencing, which refers to the quality of the sequencing reads (e.g., a depth of 20X indicates that the genome is sequenced 20 times by a sequencing machine). For the human genome, WGS became available after the completion of the Human Genome Project (HGP), which enabled the generation of a reference sequence for the whole human genome. The steps of the WGS technique are the following:
1. Preparation of isolated chromosomes
2. The DNA is sheared into small fragments
3. The DNA fragments of about 1 kilobase (1000 base pairs) are incorporated into plasmids which are cloned to render pure samples of each DNA fragment
4. The plasmid clones are sequenced by sequencing machines
5. Bioinformatic tools finally are used to link DNA fragments by their overlapping ends
Matter can be recycled, but energy cannot. Also, only 10% of the energy is passed through each trophic level.
