Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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The client who must be placed in airborne precautions is the client with a positive PPD (purified protein derivative) who has a positive x-ray for a suspicious tuberculin lesion.
Airborne precautions are steps that healthcare ability callers and stick need to attend when going into or leaving a patient's range. Airborne carefulness is for cases where one has a beginning that can spread through the air. They help stop beginning from extending so additional society forbiddance vomit.
PPD is a test used to discover if you have infection contamination. It will not cause infection contamination. This cure can be secondhand for different purposes; request your health management wage earner or druggist if you have questions. The purified protein derivative is an irritant (an essence that excites the invulnerable structure to remove or fight external entities in the party), that is introduced under the skin in the radius. After 48 to 72 hours the dose section is judged by a surgeon.
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Stop it you kid aaaaaaaaa
Answer:
b. osteoclasts
Explanation:
Osteoclasts are large multi nucleated cells. They are found in pits of the bone surface. They have many vesicles and vacuoles leading to a "foamy" cytoplasm. They also have lysosomes filled with acid phosphatase.
Osteoclasts' primary function is to breakdown bone tissue that is required for repair, maintenance and remodeling of bones. They digest the bone by secreting collagenase and acid in a process called as bone resorption. Bone resportion as a pathological response is called as osteolysis. It can be caused by inflammation, tumor and cyst.
