High levels of cortisol would normally provide negative feedback to the D)the anterior pituitary and the hypothalamus.
ACTH secretion stimulates the discharge of glucocorticoids (cortisol), mineralocorticoids (aldosterone), and androgen from the adrenal cortex.
Corticotropin-liberating hormone (CRH) is launched from the hypothalamus, which stimulates the anterior pituitary to release adrenocorticotropic hormone (ACTH). ACTH then acts on its target organ, the adrenal cortex.
Cortisol increases blood sugar by way of releasing stored glucose, at the same time as insulin lowers blood sugar. Having chronically high cortisol stages can result in continual high blood sugar (hyperglycemia). this can purpose type 2 diabetes.
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DNA synthesis occurs during the S phase, between the G1 and G2 phases of interphase. DNA replication is therefore complete before the mitotic phase begins.
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