The rocky upper layer of the solid earth is called the "lithosphere". This rocky part includes the brittle upper portion of the mantle and also of the crust. It is bounded by the atmosphere above and of the asthenosphere which is another part of the upper portion of the mantle.
<span>A. Acquired traits can be passed to offspring
Jean-Baptiste Lamarck first presented his Theory of Inheritance of Acquired Characteristics in 1801. According to his theory, if an organism changes in order to adapt to its environment, the changes are passed on the organism's offspring. Some of his proposed ideas in the theory, however, were dismissed by other scientists by experimenting and studying of genetics.</span>
Answer:
The answer is because they are in free fall. In a vacuum, gravity causes all objects to fall at the same rate. The mass of the object does not matter. If a person drops a hammer and a feather, air will make the feather fall more slowly. But if there were no air, they would fall at the same acceleration.
Explanation:
Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
Scientists publish their results and conclusions in scientific journals.
