The growth of plants and formation of land mammals characterized the paleozoic era.
If your body has developed a tolerance to a medication you're taking, it means the medication at your current dose has stopped working as effectively as it once did. It might mean your body becomes used to the medication, and you don't get the same benefits or effects as before. Drug tolerance is indicative of drug use but is not necessarily associated with drug dependence or addiction. The process of tolerance development is reversible and can involve both physiological factors and psychological factors.
