In prophase 1: Chromosomes become visible, crossing-over occurs, the nucleolus disappears, the meiotic spindle forms, and the nuclear envelope disappears. In metaphase 1: The pairs of chromosomes (bivalents) become arranged on the metaphase plate and are attached to the now fully formed meiotic spindle. The centrioles are at opposite poles of the cell. I hope my answer has come to your help. God bless and have a nice day ahead!
Usually, the procedures you should follow is using hand sanitizer or just washing your hands. That can help remove some microbes, but it is inevitable to not get any germs on you
